UMR INSERM 1246 - SPHERE
MethodS in Patients-centered outcomes
and HEalth ResEarch

INSERM Univ Nantes Univ Tours
EA4275-SPHERE
  • Home
  • Team
  • Organigram
  • Links
  • Legal
  • Contact

Research

Topics Publications In progress publications Communications

Packages

AnaQol Project PRO-online R Packages Online R-package

Life of the unit

Projects Collaborations PhD thesis Traineeships Traineeships propositions Seminars

Next seminars

Last publications

02 septembre 2020 Devos G, Clark L, Bowden-Jones H, Grall-Bronnec M, Challet G, Khazaal Y, Maurage P, Billieux J (2020) The joint role of impulsivity and distorted cognitions in recreational and problem gambling: A cluster analytic approach. Journal of Affective Disorders(127): 473-482.

19 novembre 2019 Enjalbert L, Hardouin JB, Blanchin M, Giral M, Morelon E, Cassuto E, Meurette A, Sébille V (2019) Comparison of longitudinal quality of life outcomes in preemptive and dialyzed patients on waiting list for kidney transplantation. Quality of Life Research: .

30 octobre 2019 Blanchin M, Guilleux A, Hardouin JB, Sébille V (2019) Comparison of SEM, IRT and RMT-based methods for response shift detection at item level: a simulation study. Statistical Methods in Medical Research: .

02 octobre 2019 Lascarrou J, Merdji H, Le Gouge A, Colin G, Grillet G, Girardie P, Coupez E, Dequin PF, Cariou A, Boulain T, Brule N, Frat JP, Asfar P, Landais M, Plantefeve G, Quenot J, Chakarian J, Sirodot M, Legriel S, Letheulle J, Thevenin D, Desachy A, Delahaye A, Botoc V, Vimeux S, Martino F, Giraudeau B, Reignier J, CRICS-TIGGERSEP Group (2019) Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm. N Engl J Med: doi: 10.1056/NEJMoa1906661. [Epub ahead of print].

01 octobre 2019 Bourdon M, Blanchin M, Campone M, Quéreux G, Dravet F, Sébille V, Bonnaud-Antignac A (2019) A comparison of post-traumatic growth changes in breast cancer and melanoma. Health psychology, 38(10): 878-887.

Updated

06 décembre 2019

Gildas Kubis


Situation

Poste :
Institution : UFR de Pharmacie
Téléphone : 02 40 41 28 94
Email : gildas.kubis@univ-nantes.fr
Page personnelle : http://www.univ-nantes.fr/kubis-g/0/fiche___annuaireksup/


Publications scientifiques

Articles dans une revue internationale

  • 1. Hamel JF, Sébille V, Le Neel T, Kubis G, Boyer F, Hardouin JB (2017) What are the appropriate methods for analyzing patients reported outcomes in randomized trials when data are missing?. Statistical Methods in Medical Research, 26(6): 2897-2908.

  • 2. de Bock E, Hardouin JB, Blanchin M, Le Neel T, Kubis G, Dantan E, Bonnaud-Antignac A, Sébille V (2016) Rasch-family models are more valuable than score-based approaches for analysing longitudinal PRO with intermittent missing data. Statistical Methods in Medical Research , 25(5): 2067–2087.

  • 3. de Bock E, Hardouin JB, Blanchin M, Le Neel T, Kubis G, Sébille V (2015) Assessment of score and Rasch-based methods for group comparison of longitudinal Patient-Reported Outcomes with intermittent missing data (informative and non-informative). Quality of Life Research, 24(1): 19-29.

  • 4. Hamel JF, Hardouin JB, Le Neel T, Kubis G, Roquelaure Y, Sébille V (2012) Study of different methods for comparing groups by analysis of subjective health measurements. PLoS One, 7(10): e44695.

  • 5. Blanchin M, Hardouin JB, Le Neel T, Kubis G, Blanchard C, Mirallié E, Sébille V (2011) Comparison of CTT and IRT based-approach for the analysis of longitudinal Patient Reported Outcome . Statistics in Medicine, 30(8): 825-838.

  • 6. Blanchin M, Hardouin JB, Le Neel T, Kubis G, Sébille V (2011) Analysis of longitudinal Patient-Reported Outcomes with informative and non-informative dropout: Comparison of CTT and Rasch-based methods. International Journal of Applied Mathematics & Statistics (IJAMAS), 24: SI-11A.

  • 7. Sébille V, Hardouin JB, Le Neel T, Kubis G, Boyer F, Guillemin F, Falissard B (2010) Methodological issues regarding power of Classical Test Theory (CTT) and Item Response Theory (IRT)-based approaches for the comparison of Patient-Reported Outcomes in two groups of patients - A simulation study. BMC Medical Research Methodology, 10: 24.

Publications soumise ou en révision

  • 1. (Soumis) Blanchin M, Hardouin JB, Le Neel T, Kubis G, Sébille V (2016) CTT and Rasch-based approaches for joint analysis of group and time effects of longitudinal Patient Reported Outcomes: impact of dropout mechanisms..


Participations à des projets

  • PLANIPRO : Méthodes pour la planification des études portant sur des mesures subjectives en santé


Encadrement/Accompagnement de thèses

  • Elodie de Bock : Identification de stratégies d'analyse de variables latentes longitudinales en présence de données manquantes potentiellement informatives (soutenue le 25 septembre 2014)

  • Jean-François Hamel : Identification de stratégies d'analyse de variables latentes dans les études transversales en présence de données manquantes potentiellement informatives (soutenue le 02 décembre 2014)

  • Myriam Blanchin : Développement de modèles de réponse aux items (modèles IRT) pour l'analyse de mesures subjectives en santé évaluées dans le cadre d'études longitudinales (soutenue le 10 juin 2011)


Communications scientifiques

Communications orales dans un colloque international (idpers=5)

  • 1. Blanchin M., de Bock E., Kubis G., Le Neel T., Sébille V., Hardouin J.B. Rasch and CTT-based approaches for joint analysis of group and time effects of longitudinal Patient Reported Outcomes: impact of informative and non-informative missing data. 4th International Outcome Measurement Conference, April 21-22 2015, Chicago, USA, 2015.

  • 2. de Bock E., Hardouin J.B., Blanchin M., Le Neel T., Kubis G., Dantan E., Sébille V. Analysis of longitudinal Patient-Reported Outcomes with intermittent missing data (informative and non informative): comparison of score and Rasch-based methods. 19th Annual Conference of ISOQOL, 24-27 october 2012, Budapest, Hongrie, Quality of life research 2012, 21: 42-43, 2012.

  • 3. Hamel J.F., Hardouin J.B., Le Neel T., Kubis G., Sébille V. Detection of a group effect for patients reported outcomes with Rasch models in the presence of possibly informative missing values. Congrès PROQOL: Patient Reported Outcomes and Quality of Life, 2011, Paris, France, 2011.

  • 4. Sébille V., Blanchin M., Feddag M.L., Amri S., Le Neel T., Kubis G., Guillemin F., Falissard B., Hardouin J.B. Methodological issues regarding the planning and the analyses of PRO related studies. 6th Congress of the Italian Society of Medical Statistics and Clinical Epidemiology (SISMEC), Ancona, Italia, 2011.

  • 5. Hamel J.F., Hardouin J.B., Le Neel T., Kubis G., Sébille V. Rasch models to detect a group effect for Patients Reported Outcomes with possibly informative missing data. International Workshop on "Patient Reported Outcomes and Quality of Life", Annales de l'ISUP (2011), 55(2): 49-52, 2011.

  • 6. Sébille V., Falissard B., Amri S., Feddag M.L., Le Neel T., Kubis G., Guillemin F., Hardouin J.B. Sample size determination for IRT Why should it differ from CTT?. International Workshop on "Patient Reported Outcomes and Quality of Life", Annales de l'ISUP (2011), 55(2): 73-74, 2011.

  • 7. Hardouin J.B., Falissard B., Le Neel T., Kubis G., Guillemin F., Sébille V. Comparison of classical test and item response theories in health. 31st annual conference of the international society of clinical biostatistics (ISCB), August 31-September 2, 2010, 2010.

  • 8. Blanchin M., Hardouin J.B., Le Neel T., Kubis G., Sébille V. Comparison of three methods for the analysis of longitudinal Patient Reported Outcomes. Probabilistic models for measurement in education, psychology, social science and health, June 13-16, 2010, 2010.

  • 9. Hardouin J.B., Falissard B., Le Neel T., Kubis G., Sébille V. Power with CTT and IRT based approaches for the comparison of two groups of patients. 16th International Meeting of the Psychometric Society, 2009.

  • 10. Blanchin M., Hardouin J.B., Le Neel T., Kubis G., Sébille V. Comparison of three methods for the analysis of longitudinal patient reported outcomes. 16th International Meeting of the Psychometric Society, 2009.

Poster dans un colloque international (idpers=5)

  • 1. de Bock E., Hardouin J.B., Blanchin M., Le Neel T., Kubis G., Sébille V. Analysis of longitudinal Patient-Reported Outcomes with intermittent missing data (informative and non informative): comparison of score or Rasch-based methods. International Workshop on "Patient Reported Outcomes and Quality of Life", Annales de l'ISUP (2011), 55(2): 43-46, 2011.

  • 2. Hamel J.F., Hardouin J.B., Le Neel T., Kubis G., Sébille V. Rasch models to detect a group effect for Patients Reported Outcomes. 31st annual conference of the international society of clinical biostatistics (ISCB), August 31-September 2, 2010, 2010.

  • 3. Blanchin M., Hardouin J.B., Le Neel T., Kubis G., Sébille V. Analysis of longitudinal Patient Reported Outcomes with missing data. 31st annual conference of the international society of clinical biostatistics (ISCB), August 31-September 2, 2010, 2010.

  • 4. Hamel J.F., Hardouin J.B., Le Neel T., Kubis G., Sébille V. Rasch models to detect a group effect for Patients Reported Outcomes. International Society for Clinical Biostatistics congress, 2010, France, 2010.

  • 5. Blanchin M., Hardouin J.B., Le Neel T., Kubis G., Sébille V. Comparison of three methods for the analysis of longitudinal Patient Reported Outcomes. 6th International Meeting on Recent Advances & Trends in Statistics Applied to Clinical Trials, 2009.

  • 6. Hardouin J.B., Falissard B., Le Neel T., Kubis G., Sébille V. Power with CTT and IRT based approaches for the comparison of two groups of patients. . 6th International Meeting Recent Advances & Trends in Statistics Applied to Clinical Trials, 2009.

Communications orales dans un colloque national (idpers=5)

  • 1. de Bock E., Hardouin J.B., Blanchin M., Le Neel T., Kubis G., Sébille V. Comparaison de la CTT et de l'IRT pour analyser des PRO longitudinaux comportant des données manquantes intermittentes. Chronic diseases, adaptation and perceived health: stakes and future - Young Researchers Days, 3-6 juin 2014, Nancy, 2014.

  • 2. Sébille V., Blanchin M., Guilleux A., Rouquette A., Feddag M.L., Le Neel T., Kubis G., Falissard B., Guillemin F., Hardouin J.B. How could we design studies on PRO data? The PLANIPRO project. Evaluation et analyse de la qualité de vie : nouveaux développements méthodologiques, 3-4 avril 2014, Montpellier, 2014.

  • 3. de Bock E., Hardouin J.B., Blanchin M., Le Neel T., Kubis G., Dantan E., Sébille V. Analyse de PRO recueillis de façon longitudinale et comportant des données manquantes intermittentes potentiellement informatives : comparaison de modèles issus de la théorie classique des tests et de la théorie de réponse aux items. GDR statistique et santé, 20 et 21 septembre 2012, Rennes, France, 2012.

  • 4. Blanchin M., Hardouin J.B., Le Neel T., Kubis G., Sébille V. Comparaison de trois méthodes d’analyse des variables latentes longitudinales,. 41èmes Journées de Statistique - Bordeaux, 2009.

Poster dans un colloque national (idpers=5)

  • 1. Blanchin M., Hardouin J.B., Le Neel T., Kubis G., Sébille V. Comparison of three methods for the analysis of longitudinal Patient Reported Outcomes. Epidémiologie et Biomètrie 2008, 2008.

  • 2. Blanchin M., Hardouin J.B., Le Neel T., Kubis G., Bonnaud-Antignac A., Sébille V. Comparison of three methods for the analysis of longitudinal Patient Reported Outcomes. Biostatistique et mesures subjectives en santé, Nantes, 2008, 2008.

  • 3. Hardouin J.B., Le Neel T., Kubis G., Sébille V. Comparaison de mesures issues de Patients Reported Outcomes entre deux groupes de patients : identification de facteurs influant sur la puissance. Biostatistique et mesures subjectives en santé, Nantes, 2008, 2008.



UMR INSERM 1246 - SPHERE MethodS for Patients-centered outcomes and Health ResEarches | Webmaster