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Buprenorphine prescription compliance: an original observational and longitudinal study

Auteurs

• Guillou-Landreat Morgane - Ecole doctorale Biologie-Santé - ED502 
  
  
• Sébille Véronique - PU-PH Biostatistique - Directrice de l'unité SPHERE  - Université de Nantes - UFR de Pharmacie 
  
  
• Victorri-Vigneau Caroline - MCU-PH Pharmacologie  - Université de Nantes - UFR de Médecine 
  
  
• Foucher Yohann - Maître de Conférences en Biostatistique - HDR  - UFR de médecine - Université de Nantes 
  
  
• Vénisse Jean-Luc - Professeur des Universités - Praticien Hospitalier  - UFR de Médecine - Université de Nantes - CHU Nantes 
  
  
• Jolliet Pascale - PU-PH Pharmacologie  - Université de Nantes - CHU Nantes 
  
  

Description

Nature : Articles dans une revue internationale
Thématique : Pharmacoépidémiologie
Rang : Rang A : publication porté par un membre de l'unité, dans le cadre de l'unité
Axe de recherche principal: Pharmacodépendance
Sujet : Etudes Cliniques avec ou sans financement hors PHRC et STIC

Guillou-Landreat M, Sébille V, Victorri-Vigneau C, Foucher Y, Vénisse JL, Jolliet P (2014) Buprenorphine prescription compliance: an original observational and longitudinal study. Journal of Psychoactive Drugs, 46(2): 162-7.

Lien

Abstract

INTRODUCTION: Buprenorphine is one of the main opioid dependence treatments, especially in France, where it has been widely prescribed since 1996. But it can easily be misused and its prescription has to be followed up. In the literature, we found several studies on buprenorphine, but we did not find long-term ecological follow-up studies on buprenorphine prescription and compliance. MATERIAL AND METHOD: The main purpose of this study was to define stability or instability of the prescription of buprenorphine to opiate-addicted patients. We carried out a forecast study on prescription of buprenorphine over a 10-year period, using software collecting prescription data. We performed statistical analysis of the conditions and transitions of opiate-addicted patients treated with buprenorphine along appointments. DISCUSSION/CONCLUSION: We showed that 70% of buprenorphine prescriptions are stable; we assumed that our results correspond to buprenorphine compliance. The retention in treatment was associated with a positive evolution of prescription stability. Prior criminal records were the only factor linked to instability. We showed that collecting precise prescription data in face to face appointments using software, including legal prescription rules that guide practitioners in following buprenorphine prescription compliance, seemed to be a useful method to measure buprenorphine compliance.

Publications sur le même sujet (Etudes Cliniques avec ou sans financement hors PHRC et STIC)

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• Lepère V, Vanier A, Loncar Y, Lemoine L, Vaillant J, Monsel A, Savier E, Coriat P, Eyraud D (2017) Risk factors for pulmonary complications after hepatic resection. Role of intraoperative hemodynamic instability and hepatic ischemia. , 17(1): 84.
  
  
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• Touhami S, Fardeau C, Vanier A, Zambrowski O, Steinborn R, Simon C, Tézenas du Montcel S, Bodaghi B, Le Hoang P (2016) Birdshot Retinochoroidopathy: Prognostic Factors of Long-term Visual Outcome. Americal Journal of Ophthalmology: [Epub ahead of print].
  
  
• Ali A, Carré A, Hassler C, Spilka S, Vanier A, Barry C, Berthoz S (2016) Risk factors for substances use and misuse among young people in France: What can we learn from the Substance Use Risk Profile Scale?. Drug and Alcohol Dependence, 163: 84-91.
  
  
• Brédart A, Merdy O, Sigal-Zafrani B, Fiszer C, Dolbeault S, Hardouin JB (2016) Identifying trajectory clusters in breast cancer survivors' supportive care needs, psychosocial difficulties, and resources from the completion of primary treatment to 8 months later.. Supportive Care in Cancer, 24(1): 357-366.
  
  
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• Jézéquel P, Loussouarn D, Guérin-Charbonnel C, Campion L, Vanier A, Gouraud W, Hamza L, Guette C, Valo I, Verrièle V, Campone M (2015) Gene-expression molecular subtyping of triple-negative breast cancer tumours: importance of immune response. Breast Cancer Research, 17: 43.
  
  
• Le Bourgeois A, Labopin M, Guillaume T, Foucher Y, Tessoulin B, Malard F, Ayari S, Peterlin P, Derenne S, Herry P, Cesbron A, Gagne K, Lodé L, Illiaquer M, Imbert-Marcille B, Le Gouil S, Moreau P, Mothy M, Chevallier P (2014) HHV-6 reactivation before engraftment is strongly predictive of graft failure after double umbilical cord blood allogeneic stem cell transplantation in adults. Experimental Hematology, 42(11): 945-54.
  
  
• Molinié F, Vanier A, Woronoff AS, Guizard AV, Delafosse P, Velten M, Daubisse-Marillac L, Arveux P, Tretarre B (2014) Trends in breast cancer incidence and mortality in France 1990–2008. Breast Cancer Research Treatment, 147(1): 167-75.
  
  
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Publications ayant le même axe principal de recherche (Pharmacodépendance)

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• Guillou-Landreat M, Sébille V, Victorri-Vigneau C, Grall-Bronnec M, Vénisse JL, Jolliet P (2011) Consommation d'opiacés. Un suivi systématisé au CHU de Nantes de 1998 à 2007 . Alcoologie et Addictologie, 33(1): 9-15.
  
  
• Wainstein L, Victorri-Vigneau C, Sébille V, Hardouin JB, Feuillet F, Pivette J, Chaslerie A, Jolliet P (2011) Pharmacoepidemiological characterization of psychotropic drugs consumption using a latent class analysis. International Clinical Psychopharmacology, 26(1): 54-62.
  
  
• Allain-Veyrac G, Lebreton A, Collonnier C, Jolliet P (2011) First case of symmetric drug-related intertriginous and flexural exanthema (sdrife) due to rivastigmine?. Am J Clin Dermatol, 12(3): 210-213.
  
  
• Arimone Y, Bidault I, Dutertre JP, Gérardin M, Guy C, Haramburu F, Hillaire-Buys D, Meglio C, Penfornis C, Théophile H, Valnet-Rabier MB (2011) Réactualisation de la méthode française d'imputabilité des effets indésirables des médicaments. Thérapie, 66(6): 517-525.
  
  
• Guillou-Landreat M, Victorri-Vigneau C, Grall-Bronnec M, Sébille V, Vénisse JL, Jolliet P (2011) Description of medicosocial profiles of pharmacodependent subjects consulting addictology centres using a computerized database. Encéphale, 37(6): 418-24.
  
  
• Victorri-Vigneau C, Sébille V, Gérardin M, Simon D, Pivette J, Jolliet P (2011) Epidemiological characterization of drug overconsumption: the example of antidepressants. Journal of Addictive Disease, 30(4): 342-350.
  
  
• Guillou-Landreat M, Victorri-Vigneau C, Hardouin JB, Grall-Bronnec M, Marais M, Vénisse JL, Jolliet P (2010) Can we say that seniors are addicted to Benzodiazepines?. Substance Use and Misuse, 45(12): 1988-1999.
  
  
• Jolliet P (2010) A propos des prescriptions hors-AMM. Thérapie, 65(6): 7.
  
  

Publications liées à l'axe principal de recherche (Pharmacodépendance)

• Feuillet F, Bellanger L, Hardouin JB, Victorri-Vigneau C, Sébille V (2015) On comparison of clustering methods for pharmacoepidemiological data. Journal of Biopharmaceutical Statistics, 25(4): 843-856.
  
  
• Gaboriau L, Victorri-Vigneau C, Gérardin M, Allain-Veyrac G, Jolliet P, Grall-Bronnec M (2014) Aripiprazole : a new risk factor for pathological gambling ? A report of 8 cases report. Addict Behav, 39(3): 562-5.