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25 mars 2019Empiric antimicrobial therapy for ventilator-associated pneumonia after brain injury
Auteurs
- Roquilly A
- Feuillet Fanny - Ingénieur hospitalier en Biostatistique - CHU Nantes
- Seguin P
- Lasocki S
- Cinotti R
- Launey Yoann
- Thioliere L
- Le Floch R
- Mahé P.J
- Nesseler Nicolas
- Cazaubiel T
- Rozec B
- Lepelletier D
- Sébille Véronique - PU-PH Biostatistique - Directrice de l'unité SPHERE - Université de Nantes - UFR de Pharmacie
- Mallédant Y
- Asehnoune K
Description
Abstract
Issues regarding recommendations on empiric antimicrobial therapy for ventilator-associated pneumonia (VAP) have emerged in specific populations.To develop and validate a score to guide empiric therapy in brain-injured patients with VAP, we prospectively followed a cohort of 379 brain-injured patients in five intensive care units. The score was externally validated in an independent cohort of 252 brain-injured patients and its extrapolation was tested in 221 burn patients.The multivariate analysis for predicting resistance (incidence 16.4%) showed two independent factors: preceding antimicrobial therapy ≥48 h (p<0.001) and VAP onset ≥10 days (p<0.001); the area under the receiver operating characteristic curve (AUC) was 0.822 (95% CI 0.770-0.883) in the learning cohort and 0.805 (95% CI 0.732-0.877) in the validation cohort. The score built from the factors selected in multivariate analysis predicted resistance with a sensitivity of 83%, a specificity of 71%, a positive predictive value of 37% and a negative predictive value of 96% in the validation cohort. The AUC of the multivariate analysis was poor in burn patients (0.671, 95% CI 0.596-0.751).Limited-spectrum empirical antimicrobial therapy has low risk of failure in brain-injured patients presenting with VAP before day 10 and when prior antimicrobial therapy lasts <48 h.
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Risques & Qualité, 3: 9-14.Nizard J ,Moret L ,Lombrail P ,Lajat Y (2003) Réseaux douleur : quelles formations et quelle évaluation ?. Douleurs: 64-69.Moret L ,Tequi B ,Rousselet G ,Fortun E ,Lombrail P (2002) L’hygiène des mains au CHU de Nantes : résultats d’un audit d’observance. Nosonews: 5-6.Dabouis G ,Bonnaud-Antignac A ,Bordenave S (2002) Qualité des soins et fin de vie en onco-hématologie. Le Courrier du GRASPHO, 2: 1-2.Bonnaud-Antignac A ,Bordenave S ,Dabouis G (2001) Soins curatifs, soins palliatifs, continuité des soins. La lettre de la SFAP , 14: 6-7.Victorri-Vigneau C ,Paillé C ,Joyau C ,Allain-Veyrac G ,Cosset C ,Le Pelletier A ,Jolliet P ,Nizard J ,Kuhn E [MEOPA use practices in a university hospital : Which conformity?] . Therapie. 2017 Dec;72(6):659-663. doi: 10.1016/j.therap.2017.04.003. Epub 2017 May 26.: .Gerardin M ,Guigand G ,Wainstein L ,Jolliet P ,Victorri-Vigneau C ,Clément R Evaluation of problematic psychoactive substances use in people placed in police custody.Evaluation of problematic psychoactive substances use in people placed in police custody.. J Forensic Leg Med. , 49: 24-32.Victorri-Vigneau C ,Paillé C ,Joyau C ,Allain-Veyrac G ,Cosset C ,Le Pelletier A ,Jolliet P ,Nizard J ,Kuhn E [MEOPA use practices in a university hospital: Which conformity?]. Therapie: 659-663.Gerardin M ,Guigand G ,Wainstein L ,Jolliet P ,Victorri-Vigneau C ,Clément R Evaluation of problematic psychoactive substances use in people placed in police custody.. J Forensic Leg Med: 24-32.Laforgue E ,Bulteau S ,Cholet J ,Victorri-Vigneau C ,Guitteny M ,Mauduit N ,Vanelle J ,Sauvaget A [Concordance between hospital prescriptions and recommendations in the treatment of mania].. Therapie: 327-337.Schreck B ,Wagneur N ,Caillet P ,Gerardin M ,Cholet J ,Spadari M ,Authier N ,Tournebize J ,Gaillard M ,Serre A ,Carton L ,Pain S ,Jolliet P ,Victorri-Vigneau C Cannabinoid hyperemesis syndrome: Review of the literature and of cases reportedto the French addictovigilance network.. Drug Alcohol Depend: 27-32.Cazet L ,Bulteau S ,Evin A ,Spiers A ,Caillet P ,Kuhn E ,Pivette J ,Chaslerie A ,Jolliet P ,Victorri-Vigneau C Le Moigne M ,Fournier JP ,Victorri-Vigneau C ,Dréno B Oral retinoids and depression: reply from the authors.. Br J Dermatol: .Bulteau S ,Laforgue E ,Chimot L ,Dumont R ,Loutrel O ,Etcheverrigaray F ,Victorri-Vigneau C ,Massri A ,Vanelle J ,Sauvaget A Management of Emergency Electroconvulsive Therapy in the Intensive Care Unit for Life-Threatening Psychiatric Conditions: A Case Series.. J ECT: 55-59.Victorri-Vigneau C ,Spiers A ,Caillet P ,Bruneau M ,IGNACE Group ,Challet G ,Grall-Bronnec M
Publications liées à l'axe principal de recherche (Axe non défini)
Quénéhervé L ,David G ,Bourreille ,Hardouin JB ,Rahmi G ,Neunlist M ,Brégeon J ,Coron E (2019) Quantitative assessment of mucosal architecture using computer-based analysis of confocal laser endomicroscopy in inflammatory bowel diseases. Gastrointestinal Endoscopy, 89(3): 626-636.Prudhomme T ,Dajean-Trutaud S ,Rousselet M ,Feuillet F ,Carpentier-Cheraud M ,Bonnot O ,Hyon I ,Grall-Bronnec M ,Lopez-Cazaux S ,Victorri-Vigneau C (2019) The MEOPAeDent trial protocol—an observational study of the Equimolar Mixture of Oxygen and Nitrous Oxide (EMONO) effects in paediatric dentistry. BMC Oral Health, 19: 42.Leducq S ,Giraudeau B ,Tavernier E ,Maruani A (2019) Topical use of mammalian target of rapamycin inhibitors in dermatology: A systematic review with meta-analysis. J Am Acad Dermatol, 80(3): 735-42.Goldstein C ,Giraudeau B ,Weijer C ,Taljaard M (2019) In reply: When and how should we cluster and cross over: methodological and ethical issues (letters 1 and 2). Can J Anaesth, 66(2): 239-40.Machet P ,Marcé D ,Ziyani Y ,Dumont M ,Cornillier H ,Jonville-Bera AP ,Machet L (2019) Acute generalized exanthematous pustulosis induced by iomeprol with cross-reactivity to other iodinated contrast agents and mild reaction after rechallenge with iopromide and oral corticosteroid premedication. Contact Dermatitis: doi: 10.1111/cod.13242. [Epub ahead of print].de Freminville J ,Vernier L ,Roumy J ,Patat F ,Gatault P ,Sautenet B ,Bailly E ,Chevallier E ,Barbet C ,Longuet H ,Mérieau E ,Baron C ,Buchler M ,Halimi JM (2019) Impact on renal resistive index of diabetes in renal transplant donors and recipients: A retrospective analysis of 1827 kidney transplant recipients. J Clin Hypertens (Greenwich): doi: 10.1111/jch.13492. [Epub ahead of print].Clerc H ,Tavernier E ,Giraudeau B ,Bourdais-Sallot A ,Samimi M ,Abdo I ,Maruani A (2019) Understanding the long diagnostic delay for hidradenitis suppurativa: a national survey among French general practitioners. Eur J Dermatol: doi: 10.1684/ejd.2018.3478. [Epub ahead of print].Cornillier H ,Giraudeau B ,Samimi M ,Munck S ,Hacard F ,Jonville-Bera AP ,Jegou M ,d'Acremont G ,Pham B ,Chosidow O ,Maruani A (2019) Effect of Diet in Chronic Spontaneous Urticaria: A Systematic Review. Acta Derm Venereol, 99(2): 127-32.Hanson C ,Sautenet B ,Craig J ,Chapman J ,Knoll G ,Reddy B ,Tong A (2019) Informative for Decision-making? The Spectrum and Consistency of Outcomes Following Living Kidney Donation Reported in Trials and Observational Studies. Transplantation, 103(2): 284-90.El Habnouni C ,Cornillier H ,Tauveron V ,Guyétant S ,Maruani A (2019) Rapidly Growing Tumour on the Forearm of an 83-year-old Woman: A Quiz. Acta Derm Venereol, 99(1): 121-2.Tallegas M ,Fraitag S ,Binet A ,Orbach D ,Jourdain A ,Reynaud S ,Pierron G ,Machet M ,Maruani A (2019) Novel KHDRBS1-NTRK3 rearrangement in a congenital pediatric CD34-positive skin tumor: a case report. Virchows Arch, 474(1): 111-5.Le Turnier P ,Navas D ,Garot D ,Guimard T ,Bernard L ,Tattevin P ,Vandamme Y ,Hoff J ,Chiffoleau A ,Dary M ,Leclair-Visonneau L ,Gregoire M ,Pere M ,Boutoille D ,Sébille V ,Dailly E ,Asseray N ,High-Dose Ceftriaxone CNS Infections Study Group (2019) Tolerability of high-dose ceftriaxone in CNS infections: a prospective multicentre cohort study. J Antimicrob Chemother: doi: 10.1093/jac/dky553. [Epub ahead of print].Edee A ,Tallegas M ,Jourdain A ,Listrat A ,Morel B ,Maruani A (2019) Vascular Mass of the Scalp in a Newborn: A Quiz. Acta Derm Venereol: doi: 10.2340/00015555-3131. [Epub ahead of print].Forestier B ,Anthoine E ,Reguiai Z ,Fohrer C ,Blanchin M (2019) A systematic review of dimensions evaluating patient experience in chronic illness. Health and Quality of Life Outcomes, 17(1): 19.Bonfils N ,Grall-Bronnec M ,Caillon J ,Limosin F ,Benyamina A ,Aubin H ,Luquiens A (2019) Giving room to subjectivity in understanding and assessing problem gambling: A patient-centered approach focused on quality of life. J Behav Addict: under press.Cho Y ,Sautenet B ,Gutman T ,Rangan G ,Craig J ,Ong A ,Chapman A ,Ahn C ,Coolican H ,Kao J ,Gansevoort R ,Perrone R ,Harris T ,Torres V ,Pei Y ,Kerr P ,Ryan J ,Johnson D ,Viecelli A ,Geneste C ,Kim H ,Kim Y ,Oh Y ,Teixeira-Pinto A ,Logeman C ,Howell M ,Ju A ,Manera K ,Tong A (2019) Identifying patient-important outcomes in polycystic kidney disease: an international nominal group technique study. Nephrology (Carlton): doi: 10.1111/nep.13566. [Epub ahead of print].Gabeff R ,Safar R ,Leducq S ,Maruani A ,Sarrabay G ,Touitou I ,Samimi M (2019) Successful therapy with secukinumab in a patient with generalized pustular psoriasis carrying homozygous IL36RN p.His32Arg mutation. Int J Dermatol, 58(1): e16-e17. doi: 10.1111/ijd.14293. Epub 2018 Nov 14.Lorent M ,Maalmi H ,Tessier P ,Supiot S ,Dantan E ,Foucher Y (2019) Meta-analysis of predictive models to assess the clinical validity and utility for patient-centered medical decision making: application to the CAncer of the Prostate Risk Assessment (CAPRA). BMC Med Inform Decis Mak, 19(1): .Manera K ,Johnson D ,Craig J ,Shen J ,Ruiz L ,Wang A ,Yip T ,Fung S ,Tong M ,Lee A ,Cho Y ,Viecelli A ,Sautenet B ,Teixeira-Pinto A ,Brown E ,Brunier G ,Dong J ,Dunning T ,Mehrotra R ,Naicker S ,Pecoits-Filho R ,Perl J ,Wilkie M ,Tong A (2019) Patient and Caregiver Priorities for Outcomes in Peritoneal Dialysis: Multinational Nominal Group Technique Study. Clin J Am Soc Nephrol, 14(1): 74-83.Caruana E ,Foucher Y ,Tessier P ,Frenel JS ,Classe JM ,Dantan E (2019) Patient-centered simulations to assess the usefulness of the 70-gene signature for adjuvant chemotherapy administration in early-stage breast cancer. Breast Cancer Res Treat: .Bodet-Contentin L ,Guillon A ,Boulain T ,Frat JP ,Garot D ,Le Pennec D ,Vecellio L ,Ehrmann S ,Giraudeau B ,Tavernier E ,Dequin PF (2018) Salbutamol Nebulization During Noninvasive Ventilation in Exacerbated Chronic Obstructive Pulmonary Disease Patients: A Randomized Controlled Trial. J Aerosol Med Pulm Drug Deliv: doi: 10.1089/jamp.2018.1484. [Epub ahead of print].Mebazaa A ,Geven C ,Hollinger A ,Wittebole X ,Chousterman B ,Blet A ,Gayat E ,Hartmann O ,Scigalla P ,Struck J ,Bergmann A ,Antonelli M ,Beishuizen A ,Constantin JM ,Damoisel C ,Deye N ,Di Somma S ,Dugernier T ,François B ,Gaudry S ,Huberlant V ,Lascarrou J ,Marx G ,Mercier E ,Oueslati H ,Pickkers P ,Sonneville R ,Legrand M ,Laterre P ,AdrenOSS-1 Study Investigators (2018) Circulating adrenomedullin estimates survival and reversibility of organ failure in sepsis: the prospective observational multinational Adrenomedullin and Outcome in Sepsis and Septic Shock-1 (AdrenOSS-1) study. Crit Care, 22(1): 354. doi: 10.1186/s13054-018-2243-2..Reminiac F ,Vecellio L ,Bodet-Contentin L ,Gissot V ,Le Pennec D ,Salmon Gandonnière C ,Cabrera M ,Dequin PF ,Plantier L ,Ehrmann S (2018) Nasal high-flow bronchodilator nebulization: a randomized cross-over study. Ann Intensive Care, 8(1): 128. doi: 10.1186/s13613-018-0473-8.Danet C ,Araujo M ,Bos-Thompson M ,Portolan G ,Gautier S ,Vanlemmens L ,Bonenfant S ,Jonville-Bera AP ,Cottin J ,Vial T ,Bavoux F ,Montastruc JL ,Damase-Michel C ,Benevent J ,Bourgeois-Mondon I ,Lacroix I (2018) Pregnancy outcomes in women exposed to cancer chemotherapy. Pharmacoepidemiol Drug Saf, 27(12): 1302-8.Sautenet B ,Tong A ,Chapman J ,Warrens A ,Rosenbloom D ,Wong G ,Gill J ,Budde K ,Marson L ,Josephson M ,Reese P ,Evangelidis N ,Craig J (2018) Range and consistency of outcomes reported in randomized trials conducted in kidney transplant recipients: a systematic review. Transplantation, 102(12): 2065-71.Tong A ,Manns B ,Wang A ,Hemmelgarn B ,Wheeler D ,Gill J ,Tugwell P ,Pecoits-Filho R ,Crowe S ,Harris T ,van Biesen W ,Winkelmayer W ,Levin A ,Thompson A ,Perkovic V ,Ju A ,Gutman T ,Bernier-Jean A ,Viecelli A ,O'Lone E ,Shen J ,Josephson M ,Cho Y ,Johnson D ,Sautenet B ,Tonelli M ,Craig J , SONG Implementation Workshop Investigators (2018) Implementing core outcomes in kidney disease: report of the Standardized Outcomes in Nephrology (SONG) implementation workshop. Kidney Int, 94(6): 1053-68.Chabbert-Buffet N ,Marret H ,Agostini A ,Cardinale C ,Hamdaoui N ,Hassoun D ,Jonville-Bera AP ,Lambert M ,Linet T ,Pienkowski C ,Plu-Bureau G ,Pragout D ,Robin G ,Rousset-Jablonski C ,Scheffler M ,Vidal F ,Vigoureux S ,Hédon B (2018) Contraception: CNGOF Guidelines for Clinical Practice (Short Version). Gynecol Obstet Fertil Senol, 46(12): 760-76.Bernier M ,Jonville-Bera AP (2018) Drug and food interactions with contraceptives: CNGOF Contraception Guidelines. Gynecol Obstet Fertil Senol, 46(12): 786-91.Pinier C ,Gatault P ,François M ,Barbet C ,Longuet H ,Rabot N ,Bailly E ,Buchler M ,Sautenet B ,Halimi JM (2018) Renal function at the time of nephrology referral but not dialysis initiation as a risk for death in patients with diabetes mellitus. Clin Kidney, 11(6): 762-8.Leducq S ,Vrignaud S ,Lorette G ,Herbreteau D ,Dubee V ,Martin L ,Maruani A (2018) Topical rapamycin (sirolimus) for treatment of cutaneous microcystic lymphatic malformation of the gluteal area. Eur J Dermatol: doi: 10.1684/ejd.2018.3440. [Epub ahead of print].Victorri-Vigneau C ,Spiers A ,Caillet P ,Bruneau M ,IGNACE Group ,Challet G ,Grall-Bronnec M (2018) Opioid antagonists for pharmacological treatment of gambling disorder: Are they relevant?. Curr Neuropharmacol, 16(10): 1418-1432.Perrot B ,Hardouin JB ,Grall-Bronnec M ,Challet G (2018) Typology of online lotteries and scratch games gamblers’ behaviours: a multilevel latent class cluster analysis applied to player account-based gambling data. Int J Methods Psychiatr Res. , 27(4): e1746..Caillet P ,Poirier M ,Grall-Bronnec M ,Marchal E ,Pintas C ,Wylomanski S ,Winer N ,Jolliet P ,Victorri-Vigneau C (2018) Consommation de kaolin parmi les femmes migrantes en France métropolitaine : PICA ou dépendance ?. Thérapie, 73(6): 578.Daix T ,Guerin E ,Tavernier E ,Marsaud J ,Hacan A ,Gauthier F ,Piccardo A ,Vignon P ,Feuillard J ,François B (2018) Immature Granulocytes: A Risk Factor of Infection after Cardiac Surgery. Cytometry B Clin Cytom, 94(6): 887-94.Kern L ,Godart N ,Tailhardat L ,Peguet A ,Grall-Bronnec M ,Fautrelle L (2018) A latent profile analysis revealed different categories of patients in anorexia nervosa: proposal of guidelines in adapted physical activity . Movement & Sport Sciences - Science & Motricit: under press.Montourcy M ,Hardouin JB ,Caillon J ,Leboucher J ,Rousselet M ,Grall-Bronnec M ,Challet G (2018) Typology of patients with behavioral addictions or eating disorders during a one-year period of care: exploring similarities of trajectory using growth mixture modeling coupled with latent class analysis . PlosONE, 13(11): e0207398.Petitpain N ,Argoullon L ,Masmoudi K ,Fedrizzi S ,Cottin J ,Latarche C ,Mertes P ,Gillet P , French Network of Regional Pharmacovigilance Centres (2018) Neuromuscular blocking agents induced anaphylaxis: Results and trends of a French pharmacovigilance survey from 2000 to 2012. Allergy, 73(11): 2224-33.Petitpain N ,Argoullon L ,Masmoudi K ,Fedrizzi S ,Cottin J ,Latarche C ,Mertes P ,Gillet P ,French Network of Regional Pharmacovigilance Centres (2018) Neuromuscular blocking agents induced anaphylaxis: Results and trends of a French pharmacovigilance survey from 2000 to 2012. Allergy, 73(11): 2224-33.Leyrat C ,Caille A ,Eldridge S ,Kerry S ,Dechartres A ,Giraudeau B (2018) Intervention effect estimates in cluster randomized versus individually randomized trials: a meta-epidemiological study. Int J Epidemiol: doi: 10.1093/ije/dyy229. [Epub ahead of print].Cariou B ,Challet G ,Bernard C ,Marrec M ,Hardouin JB ,Authier C ,Bach-Ngohou K ,Leux C ,Pichelin M ,Grall-Bronnec M (2018) Prevalence of hypobetalipoproteinemia and related psychiatric characteristics in a psychiatric population: results from the retrospective HYPOPSY Study. Lipids Health Dis, 17(1): 249.Rouve E ,Lakhal K ,Salmon Gandonnière C ,Jouan Y ,Bodet-Contentin L ,Ehrmann S (2018) Lack of impact of iodinated contrast media on kidney cell-cycle arrest biomarkers in critically ill patients. BMC Nephrol, 19(1): 308. doi: 10.1186/s12882-018-1091-2.Sauvaget A ,Jiménez-Murcia S ,Fernández-Aranda F ,Granero R ,Grall-Bronnec M ,Victorri-Vigneau C ,Bulteau S ,Derkinderen P ,Vanelle J ,Hakansson A ,Mestre-Bach G ,Steward T ,Menchón JM (2018) A Comparison of Treatment-Seeking Behavioral Addiction Patients with and without Parkinson's Disease. Front Psychiatry, 8: 214.Dannepond C ,Arcelus J ,Bosset J ,Porcher R ,Gautier S ,Vanelle J ,Bonnet B ,Bourgeois H ,Lacroix I (2018) Pregnancy outcomes in women exposed to cancer chemotherapy. Pharmacoepidemiol Drug Saf: doi: 10.1002/pds.4689. [Epub ahead of print].Eyzop E ,Vanier A ,Leboucher J ,Morvan M ,Poulette M ,Grall-Bronnec M ,Challet G (2018) Materialism, Financial Motives and Gambling: Examination of an Unexplored Relationship. J Gambl Stud: under press.Chantebel R ,Chesneau A ,Tavernier E ,El-Hage W ,Caille A (2018) Completeness of Descriptions of Repetitive Transcranial Magnetic Stimulation Intervention: A Systematic Review of Randomized Controlled Trials of rTMS in Depression. J ECT: doi: 10.1097/YCT.0000000000000546. [Epub ahead of print].Barbar S ,Clere-Jehl R ,Bourredjem A ,Hernu R ,Montini F ,Bruyère R ,Lebert C ,Bohé J ,Badie J ,Eraldi J ,Rigaud J ,Levy B ,Siami S ,Louis G ,Bouadma L ,Constantin JM ,Mercier E ,Klouche K ,du Cheyron D ,Piton G ,Annane D ,Jaber S ,van der Linden T ,Blasco G ,Mira J ,Schwebel C ,Chimot L ,Guiot P ,Nay M ,Meziani F , Helms J, Roger C, Louart B, Trusson R, Dargent A, Binquet C, Quenot JM ; IDEAL-ICU Trials Investigators and the CRICS TRIGGERSEP Network (2018) Timing of Renal-Replacement Therapy in Patients with Acute Kidney Injury and Sepsis. N Engl J Med, 379(15): 1431-42.Ju A ,Josephson M ,Burucoa C ,Joyeux-Faure M ,Tandé D ,Tawa A ,Fournier G ,Do-Pham G ,Casey R ,Jézéquel P ,Lochon B ,Knoll G ,Ahn C ,Hanson C ,Sautenet B ,Manera K ,Craig J ,Howell M ,Rusch E ,Tong A , SONG-Tx Lige Participation Workshop Investigators (2018)Ju A ,Josephson M ,Butt Z ,Jowsey-Gregoire S ,Tan J ,Taylor Q ,Fowler K ,Dobbels F ,Caskey F ,Jha V ,Locke J ,Knoll G ,Ahn C ,Hanson C ,Sautenet B ,Manera K ,Craig J ,Howell M ,Rutherford C ,Tong A , SONG-Tx Lige Participation Workshop Investigators (2018) Establishing a Core Outcome Measure for Life Participation: a Standardized Outcomes in Nephrology - Kidney Transplantation (SONG-Tx) Consensus Workshop Report. Transplantation: doi: 10.1097/TP.0000000000002476. [Epub ahead of print].Lauzeille D ,Guerlais M ,Sallenave-Namont C ,Etcheverrigaray F ,Broccato L ,Poisblaud Q ,Jolliet P ,Victorri-Vigneau C (2018) Medicated or not medicated hypnotic substance use: strategies in sleep disorders among patients of community pharmacy.. Fundam Clin Pharmacol: .Grall-Bronnec M ,Challet G ,Leboucher J ,Fève J ,Le Moigne M ,Derkinderen P ,Victorri-Vigneau C (2018) Hair-Pulling Disorder complicated by Skin-Picking Disorder: An Unknown Side Effect of Dopamine Replacement Therapy?. Psychiatry Clin Neurosci, 72(10): 801-802.Le Sache de Peufheiloux L ,Benamara-Lévy M ,Dionne M ,Bodemer C ,Leducq S ,Samimi M ,Maruani A (2018) Treatments and outcomes in juvenile linear scleroderma: a narrative systematic review. Eur J Dermatol, 28(5): 718-20.Hermetet C ,Saint-Martin P ,Gambier A ,Ribier L ,Sautenet B ,Rérolle C (2018) Forensic age estimation using computed tomography of the medial clavicular epiphysis: a systematic review. Int J Legal Med, 132(5): 1415-25.Daix T ,Guerin E ,Tavernier E ,Mercier E ,Gissot V ,Hérault O ,Mira J ,Dumas F ,Chapuis N ,Guitton C ,Béné M ,Quenot J ,Tissier C ,Guy J ,Piton G ,Roggy A ,Muller G ,Legac E ,de Prost N ,Khellaf M , Wagner-Ballon O, Coudroy R, Dindinaud E, Uhel F, Roussel M, Lafon T, Jeannet R, Vargas F, Fleureau C, Roux M, Allou k, Vignon P, Feuillard J, François B, Septiflux Trial Group (2018) Multicentric Standardized Flow Cytometry Routine Assessment of Patients With Sepsis to Predict Clinical Worsening. Chest, 154(3): 617-27.Taljaard M ,Weijer C ,Grimshaw J ,Ali A ,Brehaut J ,Campbell M ,Carroll K ,Edwards S ,Eldridge S ,Forrest C ,Giraudeau B ,Goldstein C ,Graham I ,Hemming K ,Hey S ,Horn A ,Jairath V ,Klassen T ,London A ,Marlin S , Marshall JC, McIntyre L, McKenzie JE, Nicholls SG, Alison Paprica P, Zwarenstein M, Fergusson DA (2018) Developing a framework for the ethical design and conduct of pragmatic trials in healthcare: a mixed methods research protocol. Trials, 19(1): 525. doi: 10.1186/s13063-018-2895-x.SRLF Trial Group (2018) Impact of oversedation prevention in ventilated critically ill patients: a randomized trial-the AWARE study. Ann Intensive Care, 8(1): 93. doi: 10.1186/s13613-018-0425-3.Sabatier R ,Nicolas E ,Paciencia M ,Jonville-Bera AP ,Madroszyk A ,Cecile M ,Braticevic C ,Duran S ,Tassy L ,Rouby F ,Micallef J ,Rousseau F (2018) Nivolumab in routine practice for older patients with advanced or metastatic non-small cell lung cancer. J Geriatr Oncol, 9(5): 494-500.Dibao-Dina C ,Angoulvant D ,Lebeau JP ,Peurois J ,Abdallah El Hirtsi K ,Lehr-Drylewicz AM (2018) Patients' adherence to optimal therapeutic, lifestyle and risk factors recommendations after myocardial infarction: Six years follow-up in primary care. PloS One, 13(9): e0202986. doi: 10.1371/journal.pone.0202986. eCollection 2018.Rumpf H ,Agard C ,Billieux J ,Bowden-Jones H ,Carragher N ,Demetrovics Z ,Higuchi S ,King D ,Mann K ,Potenza M ,Saunders J ,Abbott M ,Ambekar A ,Aricak O ,Assanangkornchai S ,Bahar N ,Borges G ,Brand M ,Chan E ,Chung T ,Derevensky J ,Kashef A ,Farrell M ,Fineberg N ,Gandin C ,Gentile D ,Griffiths M ,Goudriaan A ,Grall-Bronnec M ,Hao W , Hodgins DC, Ip P, Király O, Lee HK, Kuss D, Lemmens JS, Long J, Lopez-Fernandez O, Mihara S, Petry NM, Pontes HM, Rahimi-Movaghar A (2018) Including gaming disorder in the ICD-11: The need to do so from a clinical and public health perspective. 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Dany A ,Barbe C ,Morrone I ,Wolak A ,Reveillère C ,Hardouin JB ,Dramé M ,Sacconi S ,Bassez G ,Tiffreau V ,Richard I ,Gallais B ,Jolly D ,Novella JL ,Boyer F (2015) Construction of a Quality of Life Questionnaire for Slowly Progressive Neuromuscular Disease. Quality of Life Research, 24(11): 2615–2623 . -
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Anthoine E ,Moret L ,Regnault A ,Sébille V ,Hardouin JB (2014) Sample size used to validate a scale: a review of publications on newly-developed patient reported outcomes measures. Health and Quality of Life Outcomes, 12: 176. -
Montassier E ,Corvec S ,Hardouin JB ,Potel G ,Batard E (2014) Use of fluoroquinolones and 3rd-generation cephalosporins in the Emergency Department: a 11-year survey. European Journal of Emergency Medicine, 21(6): 442-446. Moret L ,Pourreau A ,Anthoine E ,Delmas C ,Beaudeau F ,Lombrail P (2014) Inpatients’ deprivation and their perceived social distance with physicians and nurses impact the quality and accessibility to medical information. Patient Education and Counseling: .Anthoine E ,Coutherut J ,Delmas C ,Moret L (2014) Facilitators and barriers of interprofessional collaboration regarding of perceived practices of sharing medical information and team communication. Journal of Interprofessional Care: .Grall-Bronnec M ,Sauvaget A (2014) The use of repetitive transcranial magnetic stimulation for modulating craving and addictive behaviours: A critical literature review of efficacy, technical and methodological considerations. Neuroscience and Biobehavioral Reviews, 47: 592–613.Reignier A ,Sacchetto E ,Hardouin JB ,Orsonneau J ,Le Carrer D ,Delaroche O ,Bigot-Corbel E (2014) Evaluation d’une méthode de dosage direct du LDL-cholestérol et son impact en terme de prise en charge thérapeutique. Annales de Biologie Clinique, 72(5): 593-598.Dibao-Dina C ,Caille A ,Sautenet B ,Chazelle E ,Giraudeau B (2014) Rationale for unequal randomization in clinical trials is rarely reported: a systematic review. J Clin Epidemiol, 67(10): 1070-5.-
Panouillères M ,Anota A ,Nguyen T ,Brédart A ,Bosset J ,Monnier A ,Mercier M ,Hardouin JB (2014) Evaluation properties of the French version of the OUT-PATSAT35 satisfaction with care questionnaire according to classical and item response theory analyses. Quality of life Research, 23(7): 2089-2101. Cinotti R ,Ichai C ,Orban JC ,Kalfon P ,Feuillet F ,Roquilly A ,Riou B ,Blanloeil Y ,Asehnoune K ,Rozec B (2014) Effects of tight computerized glucose control on neurological outcome in severely brain injured patients: a multicenter sub-group analysis of the randomized-controlled open-label CGAO-REA study. Critical Care, 18(5): 498.Rezvani M ,Challet G ,Keriven-Dessomme B ,Moret L ,Grall-Bronnec M (2014) Workaholism: are physicians at risk?. Occup Med (Lond), 64(6): 410-6.Asehnoune K ,Seguin P ,Allary J ,Feuillet F ,Lasocki S ,Cook F ,Floch H ,Chabanne R ,Geeraerts T ,Roger C ,Perrigault P ,Hanouz J ,Lukaszewicz A ,Biais M ,Boucheix P ,Dahyot-Fizelier C ,Capdevila X ,Mahé PJ ,Maguet P ,Paugam-Burtz C , Gergaud S, Plaud B, Constantin JM, Malledant Y, Flet L, Sebille V, Roquilly A (2014) Hydrocortisone and fludrocortisone for prevention of hospital-acquired pneumonia in patients with severe traumatic brain injury (Corti-TC): a double-blind, multicentre phase 3, randomised placebo-controlled trial. Lancet Respir Med, 2(9): 706-16.Gérardin M ,Victorri-Vigneau C ,Guerlais M ,Guillou-Landreat M ,Grall-Bronnec M ,Jolliet P (2014) Benzodiazepines consumption: does dependence vary with age?. Subst Use Misuse, 49(1): 1417-25.-
Challet G ,Hardouin JB ,Vénisse JL ,Romo L ,Valleur M ,Magalon D ,Fatseas M ,Chéreau-Boudet I ,Gorsane MA ,JEU Group ,Grall-Bronnec M (2014) Study Protocol: the JEU cohort study – transversal multiaxial evaluation and 5-year follow-up of a cohort of French gamblers. BMC Psychiatry, 14: 226. Molinié F ,Vanier A ,Woronoff AS ,Guizard AV ,Delafosse P ,Velten M ,Daubisse-Marillac L ,Arveux P ,Tretarre B (2014) Trends in breast cancer incidence and mortality in France 1990–2008. Breast Cancer Research Treatment, 147(1): 167-75.Chaigne B ,Dartigeas C ,Benboubker L ,Chaumier F ,Ertault M ,Lissandre S ,Stacoffe M ,Maillot F ,Blasco H ,Vourc'h P ,Colombat P ,Gyan E (2014) Could a citrus keep the haematologist away?. Br J Haematol, 166(2): 298-300.-
Feddag ML ,Blanchin M ,Hardouin JB ,Sébille V (2014) Power analysis on the time effect for the longitudinal Rasch model. Journal of Applied Measurement, 15(3): 292-301. -
Goffinet N ,Lecadet N ,Cousin M ,Peron C ,Hardouin JB ,Batard E ,Montassier E (2014) Increasing use of 3rd-generation cephalosporins for pneumonia in the Emergency Department : may some prescriptions be avoided ?. European Journal of Clinical Microbiology & Infectious Diseases, 33(7): 1095-1099. Combescure C ,Foucher Y ,Jackson D (2014) Meta-analysis of single-arm survival studies: a distribution-free approach for estimating summary survival curves with random effects. Statistics in Medicine, 33(15): 2521-37.Lorent M ,Giral M ,Foucher Y (2014) Net time-dependent ROC curves: a solution for evaluating the accuracy of a marker to predict disease-related mortality. Statistics in Medicine, 33(14): 2379-89.-
Sébille V ,Blanchin M ,Guillemin F ,Falissard B ,Hardouin JB (2014) A simple ratio-based approach for power and sample size determination for Rasch analysis. BMC Medical Research Methodology, 14(1): 87. -
Roulet L ,Ballereau F ,Hardouin JB ,Chiffoleau E ,Potel G ,Asseray N (2014) Adverse Drug Event Non-Recognition in Emergency Departments: An Exploratory Study on Factors Related to Patients and Drugs. Journal of Emergency Medicine, 46(6): 857-864. Cinotti R ,Dordonnat-Moynard A ,Feuillet F ,Roquilly A ,Rondeau N ,Lepelletier D ,Caillon J ,Asseray N ,Blanloeil Y ,Rozec B ,Asehnoune K (2014) Risk factors and pathogens involved in early ventilator-acquired pneumonia in patients with severe subarachnoid hemorrhage. Eur J Clin Microbiol Infect Dis, 33(5): 823-30.Guillou-Landreat M ,Sébille V ,Victorri-Vigneau C ,Foucher Y ,Vénisse JL ,Jolliet P (2014) Buprenorphine prescription compliance: an original observational and longitudinal study. Journal of Psychoactive Drugs, 46(2): 162-7.Etcheverrigaray F ,Grall-Bronnec M ,Blanchet MC ,Jolliet P ,Victorri-Vigneau C (2014) Ibuprofen dependence: a case report. Pharmacopsychiatry, 47(3): 115-117.Cholet J ,Sauvaget A ,Vanelle J ,Hommet C ,Mondon K ,Mamet J ,Cano A (2014) Using the Brief Assessment of Cognition in Schizophrenia (BACS) to assess cognitive impairment in older patients with schizophrenia and bipolar disorder . Bipolar disorders, 16(3): 326-336.-
Montassier E ,Batard E ,Massart S ,Gastinne T ,Carton T ,Caillon J ,Le Fresne S ,Caroff N ,Hardouin JB ,Moreau P ,Potel G ,Le Vacon F ,De La Cochetière MF (2014) 16S rRNA Gene Pyrosequencing Reveals Shift in Patient Faecal Microbiota During High-Dose Chemotherapy as Conditioning Regimen for Bone Marrow Transplantation.. Microbial Ecology, 67(3): 690-699. Dantan E ,Combescure C ,Lorent M ,Ashton-Chess J ,Daguin P ,Classe JM ,Giral M ,Foucher Y (2014) An original approach was used to better evaluate the capacity of a prognostic marker using published survival curves. Journal of Clinical Epidemiology, 67(4): 441-8.Roquilly A ,Seguin P ,Mimoz O ,Feuillet F ,Rosenczvei E ,Chevalier F ,Loutrel O ,Mallédant Y ,Sébille V ,Asehnoune K (2014) Risk factors for prolonged duration of mechanical ventilation in acute traumatic tetraplegic patients-a retrospective cohort study. J Crit Care, 29(2): 313.e7-13.Le Maguet P ,Roquilly A ,Lasocki S ,Asehnoune K ,Carise E ,Saint Martin M ,Mimoz O ,Le Gac G ,Somme D ,Cattenoz C ,Feuillet F ,Mallédant Y ,Seguin P (2014) Prevalence and impact of frailty on mortality in elderly ICU patients: a prospective, multicenter, observational study. Intensive Care Med: published online.Gillaizeau F ,Giral M ,Dantan E ,Dragun D ,Soulillou JP ,Foucher Y (2014) Multi-state analysis of kidney transplant recipients outcome: a semi-Markov model for studying the role of pre-transplant sensitization against Angiotensin II Type 1 receptor. Journal de la Société Française de Statistique , 155(1): 117-133.Anthoine E ,Coutherut J ,Delmas C ,Moret L (2014) Development and psychometric testing of a scale assessing the sharing of medical information and interprofessional communication: the CSI scale. BMC Health Service Research, 13: 14:126.Senage T ,Février D ,Michel M ,Pichot E ,Duveau D ,Tsui S ,Trochu JN ,Roussel J (2014) A mock circulatory system to assess the performance of continuous-flow left ventricular assist devices (LVADs): does axial flow unload better than centrifugal LVAD?. ASAIO J, 60(2): 140-7.Caillon J ,Challet G ,Grall-Bronnec M ,Allain-Veyrac G ,Jolliet P ,Grall-Bronnec M (2014) Jeux vidéo : les motivations et l'intensité de la pratique évoluent-elles avec l'âge ? Comparaison entre une population de joueurs adolescents et adultes. Arch Pediatr, 21(3): 251-257.-
Boyer L ,Baumstarck K ,Michel P ,Boucekine M ,Anota A ,Bonnetain F ,Coste J ,Falissard B ,Guilleux A ,Hardouin JB ,Loundou A ,Mercier M ,Mesbah M ,Rouquette A ,Sébille V ,Verdam M ,Ghattas B ,Guillemin F ,Auquier P (2014) Statistical challenges in quality of life and cancer: New avenues for future researches. Expert Review of Pharmacoeconomics & Outcomes Research, 14(1): 19-22. -
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Challet G ,Grall-Bronnec M ,Quistrebert-Davanne V ,Hardouin JB ,Vénisse JL (2013) Texas Hold’em Poker: a qualitative analysis of gamblers’ perceptions. Journal of Gambling Issues, 28: 1-28. -
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Pottier P ,Dejoie T ,Hardouin JB ,Le Loupps AG ,Castillo J ,Planchon B ,Bonnaud-Antignac A ,Leblanc V (2013) Effect of stress on clinical reasoning during simulated ambulatory consultations. Medical teacher, 35(6): 472-480. -
Foucher Y (2013) Modélisation et pronostic de l'évolution de pathologies chroniques : Applications en transplantation renale. , 193. Le Rhun A ,Gagnayre R ,Moret L ,Lombrail P (2013) Analysis of perceived stress by hospital caregivers in the practice of therapeutic education: implications for supervision. Glob Health Promot., 20(2): 43-47.El Arid J ,Senage T ,Toquet C ,Al Habash O ,Mugniot A ,Baron O ,Roussel J (2013) Human comparative experimental study of surgical treatment of atrial fibrillation by epicardial techniques.. J Cardiothorac Surg, 31(8): 140.-
Mantoo S ,Meurette G ,Wyart V ,Hardouin JB ,Crétolle C ,Capito C ,Sarnacki S ,Podevin G ,Lehur PA (2013) The impact of anorectal malformations on anorectal function and social integration in adulthood: report from a national database. Colorectal Disease, 15(6): e330-e335. -
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